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Inflammatory Theory


There is a theory that the underlying basis of all disease is inflammation. I believe this to be true and it is certainly true of IBS diseases I don’t think there is any disagreement about that. This leads us directly to the reason why cannabis medicine is so effective in helping to cure IBS. Cannabis is the mother of all antiinflammatories, it is a powerful antioxidant and analgesic.

The cannabis plant is made up of hundreds of components:

  1. Over 100 cannabinoids
  2. 200 terpenes or terpenoids
  3. 30 Flavonoids

We only really have any understanding of about 20 of these and that’s being generous. However those components that we do understand have amazingly healthful properties. They are neuroprotective, cancer-protective, cancer fighting, powerful anti-inflammatories and antioxidants!

Just 3 of these components are: limonene, pinene and quercetin. All three of these are
anti-inflammatory, anti-cancer, anti-bacterial, anti-viral, antioxidant,

So, we only have a partial picture of what the components of cannabis do and how they function. We have enough information to believe that many more positive attributes will be discovered with research but with just the information what we have right now we are
CERTAIN that cannabis medicine is of benefit to IBS sufferers.

Some of the Published Research
  • Cannabinoid receptor 2: potential role in immunomodulation and neuroinflammation. - 2013 - http://www.ncbi.nlm.nih.gov/pubmed/23471521 - An accumulating body of evidence suggests that endocannabinoids and cannabinoid receptors type 1 and 2 (CB(1), CB(2)) play a significant role in physiologic and pathologic processes, including cognitive and immune functions. . . . there is growing appreciation of the therapeutic potential of cannabinoids in multiple pathologic conditions involving chronic inflammation (inflammatory bowel disease, arthritis, autoimmune disorders, multiple sclerosis, HIV-1 infection, stroke, Alzheimer's disease to name a few), mainly mediated by CB(2) activation.
  • Patterns of cannabis use in patients with Inflammatory Bowel Disease: A population based analysis.- 2015 - http://www.ncbi.nlm.nih.gov/pubmed/26422462
  • Cannabis Finds Its Way into Treatment of Crohn's Disease - 2014 - https://www.karger.com/Article/FullText/356512
  • Weeding Out the Facts: The Reality About Cannabis and Crohn's Disease- 2014 - http://www.cghjournal.org/article/S1542-3565(13)01783-7/abstract
  • The holistic effects of cannabis in Crohn's disease. - 2014 - http://www.ncbi.nlm.nih.gov/pubmed/24262941
  • Cannabis for inflammatory bowel disease. - 2014 - - Mechulam - http://www.ncbi.nlm.nih.gov/pubmed/24969296
  • Cannabis induces a clinical response in patients with Crohn's disease: a prospective placebo-controlled study. - 2013 - http://www.ncbi.nlm.nih.gov/pubmed/23648372
  • Marijuana use patterns among patients with inflammatory bowel disease.- 2013 - http://www.ncbi.nlm.nih.gov/pubmed/24185313
  • Treatment of Crohn's disease with cannabis: an observational study. - 2011 - http://www.ncbi.nlm.nih.gov/pubmed/21910367
  • Marijuana use amongst patients with inflammatory bowel disease.- 2011 - http://www.ncbi.nlm.nih.gov/pubmed/21795981
  • The role of the endocannabinoid system in the pathophysiology and treatment of irritable bowel syndrome.- 2008 - http://www.ncbi.nlm.nih.gov/pubmed/18710476
  • The cannabinergic system as a target for anti-inflammatory therapies. - 2006 - http://www.ncbi.nlm.nih.gov/pubmed/16918457
  • The endocannabinoid system in the physiology and pathophysiology of the gastrointestinal tract. - 2005 - http://www.ncbi.nlm.nih.gov/pubmed/16133420